NF1/CEN17q FISH Probe
产品名称: NF1/CEN17q FISH Probe
英文名称: NF1/CEN17q FISH Probe
产品编号: FG0053
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - NF1
Approximately 260kb
Texas Red
17q11.2
- Probe 2:
Size:
Fluorophore:
Location: - CEN17q
Approximately 540kb
FITC
17q11.2
- Probe Gap:
- The gap between two probes is approximately 2,740 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Huma lung, adenosquamous cell carcinoma (FFPE) stained with NF1/CEN17q FISH Probe. Human lung, adenosquamous cell carcinoma showed no NF1 gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 4763
- Gene Name:
- NF1
- Gene Alias:
- DKFZp686J1293,FLJ21220,NFNS,VRNF,WSS
- Gene Description:
- neurofibromin 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq
- Other Designations:
- neurofibromin
- Gene Pathway
- Related Disease
- Adrenal Gland Neoplasms
- Autistic Disorder
- Cardiovascular Diseases
- Craniofacial Abnormalities
- Diabetes Mellitus, Type 2
- Edema
- Epilepsy
- Facies
- Genetic Predisposition to Disease
- Growth Disorders
- Learning Disorders
- Leukemia, Myeloid, Acute
- Multiple endocrine neoplasia
- Myelodysplastic Syndromes
- Nerve Sheath Neoplasms
- Neurofibromatosis
- Neurofibromatosis 1
- Noonan Syndrome
- Pancreatic cancer